https://bugs.winehq.org/show_bug.cgi?id=48533
--- Comment #11 from Zebediah Figura z.figura12@gmail.com --- Wine itself can run successfully in a 64-bit-only prefix, but many "64-bit" applications include 32-bit components, including installers.
If your application works in a 64-bit environment, then there is probably not much reason to try to build 32-bit Wine.