http://bugs.winehq.org/show_bug.cgi?id=6971
--- Comment #211 from Tomasz Sałaciński tsalacinski@gmail.com 2009-01-16 13:51:04 --- I think this might be the best solution - I wrote a patch that worked flawlessly with all games but only when app's window was on the center of the screen <- tested it with many applications and it worked like a charm. The only problem was the mouse dmz - I don't know how to make mouse events readable by the app if it leaves the window.
From my experience on fast moves you'll need at least ~200 pixels.