Currently if anything has created, e. g., HKLM\Software\Wow6432Node\Wow6432Node key, all the WOW keys with subkeys for HKLM\Software will be created in HKLM\Software\Wow6432Node\Wow6432Node\ instead of HKLM\Software\Wow6432Node. And then those keys cannot be found. The test in the patch demonstrates such a case.
This should fix Tom Clancy's The Division (more exactly, Ubisoft launcher setup) from Steam where Steam prerequisite setup step creates "HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Ubisoft\The Division - Steam" from a 32 bit program, which results in HKLM\Software\Wow6432Node\Wow6432Node presence (correctly), and from this point everything gets broken.