http://bugs.winehq.org/show_bug.cgi?id=19370
--- Comment #26 from Austin English austinenglish@gmail.com 2010-03-17 11:17:11 --- (In reply to comment #25)
The real workaround is setting MaxShadowSize to -1, or setting sample rate to 44100, don't bother with all these might work might not work workarounds, since it won't help you, some of them will set the sample rate to 44100 but maxshadowsize = -1 is recommended still..
Setting sample rate to 44100 would probably be enough for wine's alsa driver if it outputs to pulseaudio
Again, I tried that...still stuttered for me, using Alsa, sample rate 44100 and maxshadowsize=-1, when pulseaudio was running. It would sometimes work on the first run/after a reboot, but subsequent runs went back to hurting my ears.