http://bugs.winehq.org/show_bug.cgi?id=22784
--- Comment #17 from Nicholas van Oudtshoorn vanoudt@gmail.com 2010-05-21 03:19:11 --- Done a bit more fiddling (and looking at +relay) logs. The install seems to crash when running c:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\ISBEW64.exe
Running that manually produces exactly the same crash.