http://bugs.winehq.org/show_bug.cgi?id=25843
--- Comment #6 from Andrew Eikum aeikum@codeweavers.com 2011-10-19 14:20:30 CDT --- (In reply to comment #4)
another question: did the wine session terminate properly, or had you to kill it ?
Forgot to reply to this. It seems to happen even if Wine terminates properly, yes. I open winecfg, hit Cancel, and the settings are busted. Rerunning winecfg doesn't change anything. They are restored after opening & closing vim.