http://bugs.winehq.org/show_bug.cgi?id=16759
--- Comment #12 from Max Noel maxfnoel@gmail.com 2009-01-03 18:36:47 --- Holy crap, you're right! I just tried using a different nocd crack (I'm not sure whether posting links to nocds is all right, so I'll just say it's the one entitled "Vampire - Bloodlines v1.2 [ENGLISH/GERMAN] No-CD/Fixed EXE" you can download from GCW) and the game did launch!
That's... Interesting, to say the least. IIRC Bloodlines uses SafeDisc copy protection.