http://bugs.winehq.org/show_bug.cgi?id=30168
--- Comment #9 from Matthew matthew.rathbone@gmail.com 2012-03-18 14:04:23 CDT --- Interesting.
I was interpreting these errors based on comments on portingteam.com: http://portingteam.com/index.php/files/file/7192-mass-effect-3-fully-working...
Many users on that site report incompatibility with OSX Lion for both Mass Effect 3 and several other games.
Worth noting, that running ME3 under lion now gives me a black screen with no sound.
I know very little about Wine internals, do you have any suggestions to get around these problems?