https://bugs.winehq.org/show_bug.cgi?id=44413
--- Comment #3 from Brock Brandenberg brock@bergdesign.com --- In trying to find a workaround for this issue, I detached the 2D and 3D View tabs to make them movable and resizable windows, and it appears that the problem is related to the 3D View leaving a view rect above the 2D View window even when the 3D View window is behind the 2D View window. Some remnant from the 3D View remains on top, obscuring the 2D View and making it appear that the 2D View isn't responding properly. To work around the issue, you can make the two view tabs into windows and reduce the size of the 3D View window so that it overlaps and obscures only a tiny portion of the 2D View. This lets you effectively work in the 2D View.