https://bugs.winehq.org/show_bug.cgi?id=50739
--- Comment #5 from Gabriele gab.pulcio@gmail.com --- (In reply to Zebediah Figura from comment #4)
mmap() failed: Cannot allocate memory Failed to create permanent mapping for memfd region with ID = 2569568005 Ignoring received block reference with non-registered memfd ID = 2569568005 wine: Unhandled page fault on write access to 0000101F at address 696E6260 (thread 025c), starting debugger...
Based on a quick Internet search (e.g. https://bugzilla.redhat.com/show_bug.cgi?id=1460517) this seems to be a pulseaudio message. It suggests of course that you're running out of virtual address space. I would suggest (a) avoiding PulseAudio, (b) or configuring PulseAudio to use less shared memory, and (c) avoid DXVK, as it consumes a relatively large amount of virtual address space.
Virtual address space? Is it possible to make it more large? Because I've got 16GB of RAM, I don't know if that's releated though