http://bugs.winehq.org/show_bug.cgi?id=33832
--- Comment #6 from Austin English austinenglish@gmail.com 2013-06-24 12:43:00 CDT --- Install script executed.err:module:import_dll Library PhysXLoader.dll (which is needed by L"C:\Program Files\Steam\steamapps\common\Metro 2033\Metro2033.exe") not found err:module:LdrInitializeThunk Main exe initialization for L"C:\Program Files\Steam\steamapps\common\Metro 2033\Metro2033.exe" failed, status c0000135
does 'winetricks physx' help?