http://bugs.winehq.org/show_bug.cgi?id=18359
--- Comment #5 from Ken Sharp kennybobs@o2.co.uk 2009-05-05 18:48:41 --- (In reply to comment #4)
The obvious workaround, installing to an ext2 partition and copying over, doesn't work, at least in the case of Shaiya. The updater fails with a cryptic "Extraction failed" message and trying to run the game directly only calls the updater. Running it from the ext2 volume allows it to progress to the current GameGuard-related brick wall. Apparently IS isn't the only victim of this bug...
That's a different bug then. You need a new bug for that, if one isn't already open.