https://bugs.winehq.org/show_bug.cgi?id=40907
--- Comment #13 from David K. hevanen@googlemail.com --- Ah, perhaps my install broke during my experiments, because it launches when I use the LoL install I have on my Windows partition.
Now I'm at the bugsplat you mentioned, which is also already detailed in bug 41695: wine: Call from 0x7b43cd7c to unimplemented function api-ms-win-crt-math-l1-1-0.dll.nearbyint