http://bugs.winehq.org/show_bug.cgi?id=11180
--- Comment #8 from alan somers asomers@gmail.com 2008-07-10 11:18:59 --- Lei, you're right about ssipddp.sys. If I delete .wine and recreate it, then winecfg and notepad.exe run normally. ssipddp.sys must have come from mentor graphics pads, which I tried to install. I guess I don't know enough about windows internals to recognize that file as not belonging.