https://bugs.winehq.org/show_bug.cgi?id=57994
--- Comment #5 from Neko-san nekoNexus@protonmail.ch --- Huh, it seems that attempting to run the game in a 32-bit prefix breaks all attempts to launch the game for the rest of entire desktop session for some reason... It's apparently not strictly because of the game not being Large Address Aware; Wine is just behaving very strangely somehow.
Even if I use entirely new prefixes after the fact (32/64 bit - doesn't matter), the game will just refuse to even reach the main menu and produce outputs like the second log I shared. Baffling.