http://bugs.winehq.org/show_bug.cgi?id=18386
--- Comment #11 from Mark K markk@clara.co.uk 2012-05-22 11:42:19 CDT --- I tested "Agatha Christie: Peril at End House" with Wine 1.5.3, and this problem is still present.
The egames.com URL for the game in comment 5 no longer seems to be valid. You can instead get it from http://www.shockwave.com/gamelanding/agathaendhouse.jsp