http://bugs.winehq.org/show_bug.cgi?id=18784
--- Comment #2 from YAOMTC emailofchris@gmail.com 2009-06-04 20:06:53 --- (In reply to comment #1)
What distro? Are you using pulseaudio?
openSUSE 11.1 with KDE 4. ALSA didn't work properly before or after killing the pulseaudio process.