http://bugs.winehq.org/show_bug.cgi?id=14693
--- Comment #1 from Wont Say todurov@gmail.com 2008-07-30 02:57:30 --- When running in a virtual desktop, the Xorg process' CPU usage is very high (everything available, that is >98%), regardless of whether the game is on the current virtual desktop or not. Even if the game sits idle otherwise.
Might be a driver issue.