http://bugs.winehq.org/show_bug.cgi?id=14657
--- Comment #11 from blaise mgavl69@juno.com 2008-11-27 17:29:34 --- 'BIOSHOCK crash when loading second level'...actually, the only way I got it to load the second level was to set the resolution,textures & everything to the lowest setting - Ingame-settings and in the \profiles\username\appdata\bioshock.ini. After that you can start turning things up little by little. The shadershock ps_v2 & ps_v2b patch work quite well with my nvidia card also.