https://bugs.winehq.org/show_bug.cgi?id=49764
--- Comment #6 from subgraph93@gmail.com --- The issue also happened in Wine 5.18 and 5.19. On the Mesa side, however, the device got renamed to "lavapipe" some time ago, and more importantly, after I installed a new snapshot today, it no longer shows for me in vulkaninfo, and the virtual desktop issue is also gone. Appears the lavapipe driver is somehow no longer installed (as opposed to still installed and not causing the issue), which I'm not sure affects this Wine issue. (At least it'll be difficult for me to test any Wine changes)
This potentially relevant commit got included in the update I performed today: https://gitlab.freedesktop.org/mesa/mesa/-/commit/335132cd4dd5fd04c789bacd1c...
I apologize for maybe posting too much about this, and also possibly for submitting a questionably valid report.