http://bugs.winehq.org/show_bug.cgi?id=19039
--- Comment #8 from Vitaliy Margolen vitaliy@kievinfo.com 2009-06-25 00:13:35 --- (In reply to comment #7)
And whats so bad obout starting a game with that .desktop file?
It's not valid shell script. You can not run it that way. It's a desktop shortcut and totally meaningless to the shell. You can only "double-click" on it. Also see this for proper way of running program from the terminal: http://wiki.winehq.org/FAQ#run_from_terminal
What video driver version? Try running in virtual desktop mode. Also post output of 'xrandr' command.