http://bugs.winehq.org/show_bug.cgi?id=10061
--- Comment #4 from Austin English austinenglish@gmail.com 2007-10-16 19:47:09 --- Can you please post a link to the program you are trying to run, so others can test it?
For future reference, when attempting to test like this, you don't have to make a new user, just a new wine prefix. Either delete or move your old one, and then reinstall your program. It'll automatically make a new ~/.wine directory. Afterward, delete that directory and rename your old one back to ~/.wine. All your apps are back :-)
Finally, for future reference, list of bug severities: http://bugs.winehq.org/page.cgi?id=fields.html#bug_severity