http://bugs.winehq.org/show_bug.cgi?id=30836
--- Comment #11 from GyB gyebro69@gmail.com 2012-10-13 12:49:20 CDT --- Andrew, the patch in bug #28622 indeed fixes the audio issue in Total Overdose.
Alsa 1.0.26 on Fedora 17 Pulseaudio is not running Audio device: nVidia Corporation MCP61 High Definition Audio (rev a2)