https://bugs.winehq.org/show_bug.cgi?id=44112
--- Comment #7 from Gijs Vermeulen gijsvrm@gmail.com --- Ha, that did it. I can indeed reproduce with only one monitor active. I also experience not being to click 'Finish' on the installer because of a popup that is incorrectly positioned to let me know the icon is in the notification bar.
So it seems that something else is blocking the 'Save' dialog when only one monitor is active? That would maybe explain why the 'Save' dialog is put on a different monitor when there are multiple.