http://bugs.winehq.org/show_bug.cgi?id=19748
--- Comment #11 from Ken Phillis Jr kphillisjr@gmail.com 2010-05-31 23:16:11 --- I did some more testing, and found that this is related to the threaded rendering systems found on the steam copies of Left 4 Dead, Left 4 Dead 2 and Unreal tournament 3... The temporary fix is to disable the optimized multi-core rendering methods...
Tested against: wine-1.2-rc2-51-gbbd93e5
also, as another note, fixing the following error lines will repair the mult-core rendering techniques...
fixme:d3d_surface:IWineD3DVolumeImpl_LockBox