http://bugs.winehq.org/show_bug.cgi?id=21708
--- Comment #17 from Stefan Dösinger stefan@codeweavers.com 2012-11-18 12:18:26 CST --- Ok, so at least the swapchain present blit is broken. That should be fixable.
Depending on your game, setting this key is probably enough to get it working. My patches only matter if the game uses offscreen rendering itself. What game(s) are you trying to run?