http://bugs.winehq.org/show_bug.cgi?id=34342
--- Comment #15 from Tom a3732043@drdrb.net --- Maybe a good testing Area for low FPS is "Crucible of Eternity" dungeon http://wiki.guildwars2.com/wiki/Crucible_of_Eternity
As soon as I enter the dungeon in story mode (main hall), the FPS drops significantly. Adjusting sound quality to low help a bit. Interestingly leaving the dungeon, dying or just moving on to the first enemy room brings FPS back!
Yet just entering the dungeon doesn't trigger the memory leak.