https://bugs.winehq.org/show_bug.cgi?id=51588
--- Comment #2 from natrix mettalhunter@yahoo.com.ar --- The installation was clean with all the pack office 16. In the first installation no program was working so I was changing the USE of wine-vanilla and mesa. it is now:
wine-vanilla-6.0 (X alsa cups faudio fontconfig gecko jpeg lcms ldap mono mp3 netapi nls opencl opengl png prelink pulseaudio realtime run-exes samba scanner sdl ssl threads truetype udev udisks unwind usb v4l vkd3d vulkan xcomposite xinerama xml -capi -custom-cflags -dos -gphoto2 -gsm -gssapi -gstreamer -kerberos -mingw -odbc -openal -osmesa -oss -pcap -perl -selinux -test ABI_MIPS="-n32 -n64 -o32" ABI_S390="-32 -64" ABI_X86="32 64 -x32" ELIBC="glibc" KERNEL="-FreeBSD")
mesa-21.1.4 (X classic d3d9 dri3 egl gallium gbm gles1 gles2 llvm lm-sensors osmesa vaapi vdpau wayland xvmc zstd -debug -opencl -selinux -test -unwind -valgrind -vulkan -vulkan-overlay -xa -zink ABI_MIPS="-n32 -n64 -o32" ABI_S390="-32 -64" ABI_X86="32 64 -x32" KERNEL="linux" VIDEO_CARDS="nouveau -freedreno -i915 -i965 -intel -iris -lima -panfrost -r100 -r200 -r300 -r600 -radeon -radeonsi -v3d -vc4 -virgl -vivante -vmware")