http://bugs.winehq.org/show_bug.cgi?id=17614
--- Comment #8 from Ivan Vučica ivucica@gmail.com 2009-09-01 14:46:56 --- Found something that might be interesting in triaging this bug because I believe it's related.
1. Turn on desktop emulation mode. 2. Run the game. (Skip intro movie, of course.) 3. When you're in the main menu, you can reproduce the bug as mentioned above. 4. Focus on another window outside desktop "window". 5. Focus back on the desktop "window" (that is, click on "full-screened" RoN inside the desktop "window") 6. Notice that RoN has instead MINIMIZED. You can restore it by doubleclicking on the icon that appeared inside the desktop "window".
I don't think this affects the game after you proceed away from main menu GUI.