https://bugs.winehq.org/show_bug.cgi?id=40631
--- Comment #7 from Mathieu Comandon strider@strycore.com --- DirectX11 support is about to get much better is the following weeks or months and Denuvo will become a problem when these games become playable except for the fact that they are protected with Denuvo.
I believe this issue should remain open since there is no technical reason why Wine couldn't be compatible with Denuvo games (not saying it will be easy…) and this issue will become more widespread as we try running DX11 games in 2017.