https://bugs.winehq.org/show_bug.cgi?id=48881
--- Comment #6 from Scall scall-ebr@prosemail.net --- @soredake: I recently tried one of the games where I experienced the issue in a new prefix with case-insensitive C drive (https://www.phoronix.com/scan.php?page=news_item&px=Wine-Staging-4.10-Released -- not sure if that matters), using Wine Staging 6.4, and the issue has gone away.