https://bugs.winehq.org/show_bug.cgi?id=52393
--- Comment #51 from labre@posteo.de --- So this was obviously caused by the default portaudio backend of openal, which tries to use a Jack Audio device, probably in combination with pipewire, but since pipewire is an external process, it can’t set the flag. Possibly its library sets it or openal itself.
The workaround is to set #~/.config/alsoft.conf [General] drivers="alsa,-jack,-oss,-port,-null,-wave,"