http://bugs.winehq.org/show_bug.cgi?id=30178
--- Comment #8 from Frédéric Delanoy frederic.delanoy@gmail.com --- (In reply to karaluh from comment #7)
It is better now, however there are still some issues with the connection. Starcraft reconnects way more often that on windows.
Does using setarch work around the issue ?
e.g.
setarch i386 -3 wine SC2_executable
(I don't know the exact name of the binary)