https://bugs.winehq.org/show_bug.cgi?id=49875
--- Comment #2 from Greg G endzone102@gmail.com --- Sadly, I'm getting this every time. I ran winecfg three times in a row, and got these same messages every time.
FWIW, I'm running the Cinnamon desktop. Something in the update must be clashing with something in Wine. IDK.