https://bugs.winehq.org/show_bug.cgi?id=36546
--- Comment #20 from lilydjwg@gmail.com --- I've bought a more powerful computer, thus I can run more resource-consuming programs. However, when I want to try if version X of program Y runs fine under Wine, what winetricks commands it will need, I want to run it on tmpfs with a clean wine prefix, so I can get correct results. But many programs just refuse to install due to the special treatment with tmpfs.
Running wine in tmpfs make it fast to destroy and recreate wine prefixes many many times, faster and without making my hard disks fail any earlier.