http://bugs.winehq.org/show_bug.cgi?id=34348
--- Comment #9 from Henri Verbeet hverbeet@gmail.com 2013-08-27 01:17:41 CDT --- That message is a driver issue, but it's unlikely to prevent most applications from running. The practical effect is that display mode changes will be slightly screwed up in general, and more so in multihead setups. The easiest way to avoid that is to use the Nouveau driver, though probably at the cost of some GL performance. Other options are using an AMD or Intel GPU, or trying to convince NVIDIA to fix the drivers.
Either way, as I said before, this is unlikely to prevent most applications from running, so you probably have a different issue as well.