http://bugs.winehq.org/show_bug.cgi?id=14034
--- Comment #19 from Tobias Jakobi liquid.acid@gmx.net 2011-01-09 07:57:10 CST --- I noticed that the 'blueish artifacts on skin' issue also appears in FEAR. There the player model is affected.
Anyway, disabling GLSL support in wine also fixes the problem, so I guess it's a problem with the GLSL shader code that wine generates.