http://bugs.winehq.org/show_bug.cgi?id=23318
--- Comment #10 from GyB gyebro69@gmail.com 2011-07-23 04:43:29 CDT --- The same error message on startup in Wine-1.3.25, this time on Fedora 15.
The game support page addresses the issue here (giving only generic solutions): http://bussimulator.icebytesgames.de/index.php?id=105&L=1
Google also returns several hits about the problem, posted by Windows users on different forums. Seemingly a problem in the game itself.