http://bugs.winehq.org/show_bug.cgi?id=21873
--- Comment #3 from Vitaliy Margolen vitaliy@kievinfo.com 2010-02-26 20:42:58 ---
When dmix is enabled, alsa corrupts the sound output (even for other
applications). I don't see anything about Wine there. Does using native Linux programs with alsa and dmix work fine?
What distro? Have you compiled kernel yourself? If so, did you enable old API compatibility for ALSA?