https://bugs.winehq.org/show_bug.cgi?id=52391
--- Comment #11 from poweroverwhelming982@gmail.com --- (In reply to Sveinar Søpler from comment #10)
Looks like you're right. I checked Skyrim's resource files and it uses .xwm for music, plain old .wav for sounds, and their own .fuz format for voices, which contains a .xwm and a lipsync file. So I can confirm that this is a WMA playback issue, not someting related to audio mixing as I initially assumed. I can also confirm that winetricks xact works here as well. I might try fiddling with the faudio patches, thanks for the additional info.