http://bugs.winehq.org/show_bug.cgi?id=10487
--- Comment #6 from soxs schuster.bernhard@googlemail.com 2008-05-27 04:36:07 --- lostcoast\hl2.exe: symbol.c:403: symt_normalize_function: Assertion `func' failed.
this seems to be the cause.
Tried to run HL2 Lost Coast on wine-1.0-rc2 and having installed ati drivers 8.5