http://bugs.winehq.org/show_bug.cgi?id=17357
--- Comment #3 from Andrew Nguyen arethusa26@gmail.com 2009-02-13 02:25:26 --- This isn't a regression as far as I can tell. I tested with Wine 1.0 and 1.0.1, which has the same problem. Enabling the virtual desktop seems to work around the mouse input issue.