http://bugs.winehq.org/show_bug.cgi?id=18303
--- Comment #16 from Walther Bans waltherbans@yahoo.de 2012-09-16 15:49:39 CDT --- Sorry for this delayed answer :/
Yes, I used a clean .wine directory.
And I can reproduce Owen Rudge's observation: Acrobat crashes when choosing "edit" in the menu while a PDF is opened. I didn't notice this earlier because there was no need to open edit/ settings with a pdf opened.