https://bugs.winehq.org/show_bug.cgi?id=42820
--- Comment #9 from Pekka Helenius fincer89@hotmail.com --- I configured the patch for Wine 2.18 Staging. I did multiple test runs with and without the patch for Witcher 3. I have not played the game so much, just actually the initial room and the first staircase. I can't tell any differences. I did testing with ROTTR, too. No major differences either.
Disclaimer: I don't know whether the current form of the patch code applies good enough to current Wine Staging version due to multiple D3D11 commits after the May when the patch was initially published. Wine devs have better understanding of this topic.
I may add the re-adapted patch & debugging stuff later, if needed.