http://bugs.winehq.org/show_bug.cgi?id=22091
--- Comment #33 from adamjacobs173@googlemail.com 2011-04-16 11:17:58 CDT --- (In reply to comment #30)
Affects Mass effect 1. Using the fix by Sam works around it.
It did affect Mass Effect 2 as well, but yeah, Sam's patch worked for me.