http://bugs.winehq.org/show_bug.cgi?id=11952
--- Comment #3 from Timo-Heikki Mäkelä imaxfun@gmail.com 2008-03-09 15:49:31 --- Which version of notepad++ do you use? And which distro?
Have you tried the same version with earlier versions of Wine successfully? If yes, could you run a regression test to find out what went wrong, please. That would help solving this a lot. http://wiki.winehq.org/RegressionTesting