http://bugs.winehq.org/show_bug.cgi?id=21269
--- Comment #4 from Jeff Zaroyko jeffz@jeffz.name 2010-01-06 20:45:03 --- (In reply to comment #3)
I used the same command line that is used by the application launcher that was created by wine, which i usually use to start the game.
That's not the same as using the launcher. The application launcher usually sets a working directory, you will have to do this manually.
http://wiki.winehq.org/FAQ#head-8d8c06cf7fb33269c085a07531b61e5c730566e0