http://bugs.winehq.org/show_bug.cgi?id=34011
--- Comment #7 from Xavier Vachon xvachon@gmail.com 2013-11-15 18:16:30 CST --- (In reply to comment #6)
As I've been looking for more information regarding the issue and potential workarounds, there seems to be a consensus that this is only an issue for users with AMD/ATi graphics cards.
If that is so, that would make this not a wine issue, unfortunately.
What graphics card do you guys have? I have a Radeon HD 7870 (PCIe).
I have an NVIDIA 550 TI, so it affects NVIDIA too. Setting UseGLSL to disabled makes the game playable, but even then I often die because of the lag when I face unique bosses or large group of creatures.