https://bugs.winehq.org/show_bug.cgi?id=19661
--- Comment #19 from Todd Chester ToddAndMargo@zoho.com --- (In reply to Todd Chester from comment #18)
5.22 runs approach fine after setting the path correctly in my virtual Fedora 33 machine.
Well, that is until I try to open a database or create a new one. Then I get "Error on LSIOpen". Happens of 5.18. and 5.22 as well. But ONLY on my virtual machine. The host works fine on 5.18
Figured that one out. You have to go into the Smart Suite installer, Modify, and ONLY install the ODBC drivers