http://bugs.winehq.org/show_bug.cgi?id=32832
--- Comment #10 from Austin English austinenglish@gmail.com 2013-01-30 13:24:13 CST --- (In reply to comment #9)
Maybe suggesting that users of wine are in a wine group, making .wine owned by group wine and sgid and applying a group quota on wine could be a viable solution?
That's a system administrator decision. Wine expects the WINEPREFIX to be owned/controlled by the user running it, not for them to be shared between multiple users/groups.